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5 Roots, Prefixes and Suffixes

Anatomical terms are made up of roots, prefixes and suffixes. The root of a term often refers to an organ, tissue or condition, whereas the prefix or suffix often describes the root. For example, in the disorder hypertension, the prefix “hyper-” means “high” or “over,” and the root word “tension” refers to pressure so the word “hypertension” refers to abnormally high blood pressure.

The root is the base part of the word, generally found in the ‘middle’ of the word itself. Some common roots that might be familiar include ‘auto’ as in ‘self’, like an ‘automatic’ car, or ‘phobia’ as in ‘fear’, like ‘claustrophobia‘. Roots form the basis of new words through the addition of prefixes and suffixes. A prefix is the syllable added to the beginning of the word, or the beginning of a root. Prefixes include words such as ‘anti-‘ which means ‘against’ like antisocial, or ‘sub’ as in ‘below’ or ‘beneath’, like a ‘submarine’. Suffixes, in turn, are the letters, or syllables, found added at the end of a word or a word root. Suffixes are used to change the meaning or a function of a word, for example changing present tense to past tense. Some common suffixes include ‘-er‘ which means someone who carries out an action, such as a ‘teacher‘ or ‘dancer‘, or ‘-ful’ which means ‘full of’ or ‘notable of’, for example ‘wonderful‘ or ‘beautiful‘.

There are some common roots, prefixes and suffixes used throughout medical terminology which are primarily derived from Latin or Greek languages. Some examples of common medical roots, prefixes and suffixes are listed in the tables below.

Roots
Component Meaning Example
Blast- germ, immature cell blastoma = a cancer made of immature cells
Carcin- Cancer carcinogenic = cancer causing
Cardio- heart cardiotoxicity = toxicity to the heart
Cyto- cell cytotoxic = toxic to the cell
Derma- skin dermatitis = inflammation of the skin
Histio- tissue histology = study of tissue
Hepati- liver hepatoblastoma = liver cancer
Malign- bad / harmful malignant = growing, spreading
Nephro- kidney nephrotoxic = harmful to the kidneys
Neuro- nerves neuroblast = an immature nerve cell
Onco- mass / tumour oncology = the study of cancer
Osteo- bone / bony tissue osteosarcoma = bone cancer
Paed- child paediatric oncology = study of childhood cancer
Sarco- tissue sarcoma = tumour of bone, muscle, or connective tissue
Toxo- poison toxicology = study of poisons

Suffixes
Component Meaning Example
-aemia condition of blood leukaemia = cancer of blood cells
-ectomy excision / removal nephrectomy = excision of a kidney
-itis inflammation hepatitis = inflammation of the liver
-ology study / science of cytology = the study of cells
-oma tumour retinoblastoma = tumour of the eye
-pathy disease neuropathy = disease of the nervous system
-osis disease /condition necrosis = dying cells

Prefixes
Component Meaning Example
An-, A- without / lack of anaemia = lack of red blood cells
Ab- away from abnormal = away from the normal
Ad- near / toward adrenal gland = gland near to the kidney
Bi- two / both bilateral Wilm's = tumour in both kidneys
Dys- difficult / painful dysfunction = not working properly
Ecto- outside ectopic pregnancy = outside the uterine cavity
Endo inside endoscope = an instrument to look inside the body cavities or organs
Epi- upon epidermis = the outer layer of skin
Hyper- excessive / above hyperglycaemia = excessive blood sugar levels
Hypo- beneath / below hypodermic = injection below the skin
Inter- between intercostal = between the ribs
Intra- within / inside intravenous = into a vein
Para- beside, about, near parathyroid = beside the thyroid gland
Peri- around pericardium = membrane around the heart
Pre- before prenatal = before birth
Post- after post surgical stage = stage after surgery
Sub- under / below submucosa = tissue below mucus membrane
Syn- together with syndrome = group of symptoms occurring together

 

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